Subject(s)
Humans , Male , Female , Adult , Arginase/metabolism , Arthritis, Reactive/microbiology , Arthritis, Reactive/virology , Leukocytes, Mononuclear/microbiology , Leukocytes, Mononuclear/virology , Nitric Oxide Synthase Type III/metabolism , Nitric Oxide/metabolism , Arthritis, Reactive/complications , Arthritis, Reactive/immunology , Bacterial Infections/complications , Bacterial Infections/immunology , Bacterial Infections/microbiology , Case-Control Studies , Chlamydia trachomatis/classification , Chlamydia trachomatis/isolation & purification , Female Urogenital Diseases/complications , Female Urogenital Diseases/immunology , Female Urogenital Diseases/microbiology , Female Urogenital Diseases/virology , Gastrointestinal Diseases/complications , Gastrointestinal Diseases/immunology , Gastrointestinal Diseases/microbiology , Gastrointestinal Diseases/virology , Hepacivirus/classification , Hepacivirus/isolation & purification , Hepatitis B virus/classification , Hepatitis B virus/isolation & purification , Hepatitis/complications , Hepatitis/immunology , Hepatitis/virology , Leukocytes, Mononuclear/immunology , Male Urogenital Diseases/complications , Male Urogenital Diseases/immunology , Male Urogenital Diseases/microbiology , Male Urogenital Diseases/virology , Nasopharyngeal Diseases/complications , Nasopharyngeal Diseases/immunology , Nasopharyngeal Diseases/microbiology , Nasopharyngeal Diseases/virology , Primary Cell Culture , Streptococcus pyogenes/classification , Streptococcus pyogenes/isolation & purificationABSTRACT
BACKGROUND/AIMS: Patients with irritable bowel syndrome (IBS) are more likely to experience certain urinary symptoms. The aims of this study were to investigate the association between lower urinary tract symptoms (LUTS) and IBS, and to determine their impact on the quality of life. METHODS: E-mails were sent to 23,594 men who were registered at an internet survey company. Subjects were requested to fill out the questionnaires regarding IBS and LUTS assessed by the International Prostate Symptom Score (IPSS). RESULTS: Among 601 subjects (mean age, 35.5+/-8.4) included in the final analysis, 118 (19.6%) fulfilled the Rome II criteria for the diagnosis of IBS. The total mean IPSS of IBS subjects was 9.6, which was significantly higher than the 7.0 of non-IBS subjects (p<0.01). When IPSS was subcategorized into mild, moderate, and severe symptom categories, the proportions with the moderate and severe symptoms among IBS subjects were 33.9% and 13.6% respectively, which were significantly higher than those of non-IBS subjects; (26.9 and 5.2%) (p<0.01). In multivariate analysis, statistically significant association was found between IBS and moderate to severe LUTS (OR, 1.91; 95% CI, 1.27-2.88). IBS subjects also showed a poorer quality of life score than non-IBS subjects (2.24 vs. 1.65, p<0.001). CONCLUSIONS: LUTS in adult men with IBS are more severe and have a more negative impact on the quality of life than in non-IBS subjects.
Subject(s)
Adult , Humans , Male , Middle Aged , Age Factors , Internet , Irritable Bowel Syndrome/complications , Male Urogenital Diseases/complications , Quality of Life , Surveys and QuestionnairesABSTRACT
Melioidosis is an infectious disease caused by Burkholderia pseudomallei. It occurs predominantly in tropical regions. The manifestations are protean which include pneumonia, visceral abscesses, septic arthritis, osteomyelitis, acute suppurative and chronic granulomatous lesions with involvement of almost all organ systems. Fulminant sepsis is much more common and is associated with high mortality. Hence prompt recognition and early treatment is warranted. We report unusual presentations of urinary tract melioidosis in two diabetic men.
Subject(s)
Adult , Diabetes Complications/diagnosis , Humans , Male , Male Urogenital Diseases/complications , Melioidosis/complications , Middle AgedABSTRACT
OBJECTIVE: Klippel-Trenaunay-Weber syndrome (KTWS) is a congenital condition characterized by vascular malformations of the capillary, venous and lymphatic systems associated to soft tissue and bone hypertrophy in the affected areas. This syndrome may involve bladder, kidney, urethra, ureter and genitals. We report the treatment of 7 KTWS patients with urogenital involvement. MATERIALS AND METHODS: From 1995 to 2005, 7 patients with KTWS were evaluated and the charts of these patients were reviewed. RESULTS: PatientsÆ median age was 19-years (range 4 to 46-years) and only 1 was female. The clinical presentation included genital deformities in 3 cases, hematuria in 2 and urethrorragia in 2, one of which associated with cryptorchidism and phimosis. Three patients had an association of pelvic and genital malformations, including 2 patients with hematuria due to vesical lesions and 1 patient with left ureterohydronephrosis due to a pelvic mass. Two patients had urethral lesions. Treatment included endoscopic laser coagulation for 1 patient with recurrent hematuria and 1 patient with urethrorrhagia, pelvic radiotherapy for 1 patient with hematuria and circumcision in 2 patients with genital deformities. One patient required placement of a double-J catheter to relieve obstruction. Hematuria and urethrorragia were safely and effectively controlled with laser applications. Circumcision was also effective. The patient treated with radiotherapy developed a contracted bladder and required a continent urinary diversion. CONCLUSIONS: Urogenital involvement in patients with KTWS is not rare and must be suspected in the presence of hematuria or significant cutaneous deformity of the external genitalia. Surgical treatment may be warranted in selected cases.